Leslie Bernard Hunt: 1906–1987

Evolvability LESLIE

Living organisms function in accordance with complex mechanisms that operate in different ways depending on conditions. Darwin’s theory of evolution suggests that such mechanisms evolved through variation guided by natural selection. However, there has existed no theory that would explain quantitatively which mechanisms can so evolve in realistic population sizes within realistic time periods, ...

Leslie Matthews

Bernard Wood

Photo: Courtesy of Bill Kimbel. The benefit could also apply to amyotrophic lateral sclerosis (ALS). While the mechanism by which the gene therapy triggers these beneficial effects remains to be elucidated, this unexpected finding suggests that even gene therapy for rare specific gene defects may in some cases have broader applicability. Recent developments have broadened the scope of gene ther...

Leslie B. Vosshall

adhesion. We used urushiol, the active ingredient in poison ivy, as an agonist for aggregation. Of course, I never wore anything practical like pants or a lab coat and got a raging urushiol rash all over my legs. When I wasn’t tampering with sea urchin reproduction or dripping urushiol on my thighs, I hung out with students and faculty in the legendary MBL summer courses and went to a lot of gr...

3 Evolvability LESLIE

Living organisms function in accordance with complex mechanisms that operate in different ways depending on conditions. Darwin’s theory of evolution suggests that such mechanisms evolved through variation guided by natural selection. However, there has existed no theory that would explain quantitatively which mechanisms can so evolve in realistic population sizes within realistic time periods, ...